Guided by Experience. Driven by Innovation.

Founded in Basel, Switzerland (the global epicenter of pharmaceutical innovation), SunRegen Healthcare AG was established with a singular, unwavering mission.

SunRegen Healthcare AG was founded in Basel, Switzerland with one purpose: to discover and develop revolutionary therapies that protect and rescue neurons. Our executive leadership and scientific advisory boards are comprised of seasoned drug hunters, clinical development specialists, and business operators who have successfully navigated complex molecules from discovery through global commercialization at the world's leading pharmaceutical organizations, including Novartis, Roche, Alcon, and Allergan.

Beginning with the discovery of SBC003's neuroprotective mechanism in 2016, SunRegen has systematically built a platform validated across multiple animal models, recognized by elite innovation bodies including Johnson & Johnson's JLABS, the European Union's SME Instrument, and the Swiss Federal Innovation Agency (Innosuisse). Today, we are advancing SBC003 through CMC and GLP toxicology studies toward Phase I/II clinical trials, starting with Retinitis Pigmentosa and expanding into Dry AMD and broader CNS neurodegeneration.

Our Impact

Making a Global Difference

Numbers that showcase our commitment to transforming neurodegenerative disease treatment

+

Pipeline Programs

Active indications

CHF M

Innovation Grant

Innosuisse funding

+

Awards & Recognition

International honors

+

Years Expertise

Core Team average

M+

RP Patients Worldwide

M+

Projected AMD by 2040

M+

Global Patients

Affected by AMD

Vision

A future where neurodegeneration is no longer an irreversible sentence. We envision a world where orally bioavailable, disease-modifying neuroprotective therapies are standard of care, halting photoreceptor apoptosis, clearing toxic protein aggregates, and restoring function across retinal and central nervous system conditions.

Mission

To develop first-in-class, orally bioavailable lipid therapeutics that protect and rescue neurons by targeting the neuroglobin pathway and restoring cellular proteostasis. We begin with the most critical unmet needs in retinal neurodegeneration, Retinitis Pigmentosa and Dry AMD, and expand to tackle the broader landscape of CNS neurodegenerative diseases including Alzheimer's, Parkinson's, and ALS.

What we stand for

Our Values

Six principles guide every decision SunRegen makes — from how we run a preclinical experiment to how we structure a partnership.

Click through the stack to explore each one.

Meet Our Leadership

Hechang "David" Guan

Hechang "David" Guan

CEO & Managing Director

Hechang "David" Guan

CEO & Managing Director

David holds a Master's degree in Electrical Engineering and brings a decade of senior management experience with multinational technology conglomerates including Honeywell and HP to the table. As an entrepreneur, he has a proven track record in international capital raising and cross-cultural team leadership, having successfully navigated SunRegen through multiple funding rounds and strategic corporate partnerships across Switzerland, Asia, and North America.

Dr. Yuhong Dong

Dr. Yuhong Dong

Founder, CSO & Chairman

Dr. Yuhong Dong

Founder, CSO & Chairman

Dr. Dong holds both a Medical Degree and a Ph.D. in infectious disease from Beijing University and brings over 20 years of expertise in drug research and development across pharma and academia. A former Senior Medical Scientific Expert at Novartis Basel Headquarters, she is a four-time Novartis Award recipient with 30+ peer-reviewed publications. The discoverer of SBC003's neuroprotective mechanism, she pioneered SunRegen's phenotype-to-pathway reverse-engineering approach to drug discovery.

Dr. Chiho "Hubert" Wong

Dr. Chiho "Hubert" Wong

Board Member

Dr. Chiho "Hubert" Wong

Board Member

Dr. Chiho "Hubert" Wong is a registered general practitioner in both Hong Kong and mainland China. He holds a Master of Philosophy in Surgical Sciences and a Master of Science in Health Service Management from the Chinese University of Hong Kong. A dual fellow of the Hong Kong College of Health Service Executives and the Australian College of Healthcare Management, he brings extensive expertise to healthcare leadership.

Our Team

Our leadership and scientific advisory team represent decades of hard-won drug development expertise across the world's most prestigious pharmaceutical organizations. The executive team has proven experience navigating molecules through preclinical, IND, and clinical development. Our scientific advisory board includes a former VP & Global Head of Preclinical Safety at Novartis (40+ new drug registrations), the former Head of Retina Discovery at Allergan and VP of Retinal R&D at Alcon, a former leading Alzheimer's neuroscience researcher at Novartis recognized as an Outstanding Scientist, and a Principal Scientist at the Schepens Eye Research Institute / Harvard Medical School. This institutional pedigree directly de-risks the SBC003 development pathway.

Scientific Advisory Board

World-class experts guiding our neuroprotective research from discovery through clinical translation.

Dr. Philip Bentley

Dr. Philip Bentley

DMPK and Toxicology Lead

40+ years in drug metabolism, toxicology, and preclinical safety. Former VP & Global Head of Preclinical Safety at Novartis, instrumental in managing over 40 successful new drug registrations across oncology, CNS, and respiratory indications.

Dr. Thomas Hohman

Dr. Thomas Hohman

Ophth Drug Development Expert

30+ years overseeing flagship ophthalmology therapy development. Former Head of Retina Discovery at Allergan and VP of Retinal R&D at Alcon. Expert in age-related macular degeneration and geographic atrophy therapeutic development.

Dr. Hans-Jürgen Pfannkuche

Dr. Hans-Jürgen Pfannkuche

Head of R&D

35+ years in clinical pharmacology, rigorous pharmacovigilance, and drug safety operations. Former expert at Novartis Pharma AG and Sandoz, leading projects spanning Good Laboratory Practice (GLP) safety studies and global drug registration affairs.

Dr. Matthias Staufenbiel

Dr. Matthias Staufenbiel

Neurological Strategic Development Lead

24+ years in leading positions at Novartis and Sandoz Preclinical Neuroscience Research. Recognized as an Outstanding Scientist at Novartis for pivotal contributions to Alzheimer's disease drug development. Co-author of 200+ peer-reviewed publications.

Dr. Kin-Sang (Anson) Cho

Dr. Kin-Sang (Anson) Cho

Head of R&D

Principal Scientist at the Schepens Eye Research Institute of Mass. Eye and Ear, and Instructor in Ophthalmology at Harvard Medical School. Leading expert in mechanisms of retinal degeneration and regeneration, including glaucoma and Retinitis Pigmentosa.

Dr. Philip Bentley

Dr. Philip Bentley

DMPK and Toxicology Lead

40+ years in drug metabolism, toxicology, and preclinical safety. Former VP & Global Head of Preclinical Safety at Novartis, instrumental in managing over 40 successful new drug registrations across oncology, CNS, and respiratory indications.

Dr. Thomas Hohman

Dr. Thomas Hohman

Ophth Drug Development Expert

30+ years overseeing flagship ophthalmology therapy development. Former Head of Retina Discovery at Allergan and VP of Retinal R&D at Alcon. Expert in age-related macular degeneration and geographic atrophy therapeutic development.

Dr. Hans-Jürgen Pfannkuche

Dr. Hans-Jürgen Pfannkuche

Head of R&D

35+ years in clinical pharmacology, rigorous pharmacovigilance, and drug safety operations. Former expert at Novartis Pharma AG and Sandoz, leading projects spanning Good Laboratory Practice (GLP) safety studies and global drug registration affairs.

Dr. Matthias Staufenbiel

Dr. Matthias Staufenbiel

Neurological Strategic Development Lead

24+ years in leading positions at Novartis and Sandoz Preclinical Neuroscience Research. Recognized as an Outstanding Scientist at Novartis for pivotal contributions to Alzheimer's disease drug development. Co-author of 200+ peer-reviewed publications.

Dr. Kin-Sang (Anson) Cho

Dr. Kin-Sang (Anson) Cho

Head of R&D

Principal Scientist at the Schepens Eye Research Institute of Mass. Eye and Ear, and Instructor in Ophthalmology at Harvard Medical School. Leading expert in mechanisms of retinal degeneration and regeneration, including glaucoma and Retinitis Pigmentosa.

Dr. Philip Bentley

Dr. Philip Bentley

DMPK and Toxicology Lead

40+ years in drug metabolism, toxicology, and preclinical safety. Former VP & Global Head of Preclinical Safety at Novartis, instrumental in managing over 40 successful new drug registrations across oncology, CNS, and respiratory indications.

Dr. Thomas Hohman

Dr. Thomas Hohman

Ophth Drug Development Expert

30+ years overseeing flagship ophthalmology therapy development. Former Head of Retina Discovery at Allergan and VP of Retinal R&D at Alcon. Expert in age-related macular degeneration and geographic atrophy therapeutic development.

Dr. Hans-Jürgen Pfannkuche

Dr. Hans-Jürgen Pfannkuche

Head of R&D

35+ years in clinical pharmacology, rigorous pharmacovigilance, and drug safety operations. Former expert at Novartis Pharma AG and Sandoz, leading projects spanning Good Laboratory Practice (GLP) safety studies and global drug registration affairs.

Dr. Matthias Staufenbiel

Dr. Matthias Staufenbiel

Neurological Strategic Development Lead

24+ years in leading positions at Novartis and Sandoz Preclinical Neuroscience Research. Recognized as an Outstanding Scientist at Novartis for pivotal contributions to Alzheimer's disease drug development. Co-author of 200+ peer-reviewed publications.

Dr. Kin-Sang (Anson) Cho

Dr. Kin-Sang (Anson) Cho

Head of R&D

Principal Scientist at the Schepens Eye Research Institute of Mass. Eye and Ear, and Instructor in Ophthalmology at Harvard Medical School. Leading expert in mechanisms of retinal degeneration and regeneration, including glaucoma and Retinitis Pigmentosa.

Validated by Industry Leaders

Awards & Recognition

From Basel incubators to global pharma — a track record of independent validation across our journey.

  • 2023
    JLABS Shanghai by J&J

    Enrolled into JLABS Shanghai by J&J in 2023

  • 2018-2019
    Seal of Excellence SME Instrument

    Seal of Excellence SME Instrument of EU Horizontal 2020 Program in 2018-2019

  • 2018
    BIO-Europe Startup Slam Winner

    Winner of the Startup Slam Competition at the 2018 BIO-Europe

  • 2017
    IMAGINE IF Global Top 20 Finalist

    Winner of IMAGINE IF Global Top 20 Finalists in 2017

  • 2017
    BaseLaunch

    Enrolled Into BaseLaunch, A Top Swiss BioIncubator in 2017

  • 2017
    Innosuisse Coaching

    Coaching Program by Innosuisse, A Swiss Federal Innovation Agency

Strategic Partnerships

SunRegen Healthcare AG is validated by and actively collaborating with elite international innovation bodies and pharmaceutical development organizations. Our partnerships span the full drug development continuum, from scientific discovery to clinical execution.

Johnson & Johnson JLABS

JLABS@Shanghai residency provides access to J&J's global pharmaceutical development network and manufacturing expertise.

Innosuisse & EU SME Instrument

Recognized by the Swiss Federal Innovation Agency (Innosuisse) and the European Union's Horizon 2020 program with the Seal of Excellence.

Academic Institutions

Research collaborations with EPFL's Brain Mind Institute, University of Zurich (UZH), and the Schepens Eye Research Institute at Harvard Medical School.

Join Our Team

We welcome experienced scientists from the CNS and retinal field, or industry experts for preclinical/clinical development, to contact us. Please send your CV and cover letter to [email protected].